01 / OVERVIEW
What it is
NAD+ is a coenzyme — a helper molecule — present in every cell. It is not a peptide, but it is often offered alongside peptide therapies as part of healthy-aging care.
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NAD+
Nicotinamide adenine dinucleotide
A coenzyme found in every cell that supports energy production and cellular repair, and declines with age.
- STATUS
- Not FDA-approved as a treatment. Available as a compounded medication prepared by a licensed pharmacy.
- FORMS
- Injection · IV infusion · Nasal spray or other compounded forms
- ACCESS
- Prescription only · Telehealth in all 50 states
KEY TAKEAWAYS
- Essential to how cells turn food into energy
- Levels naturally decline with age
- Human evidence for supplementing NAD+ directly is still early
02 / MECHANISM
How it works
NAD+ helps mitochondria produce energy and is used by enzymes involved in DNA repair and cellular stress responses. Research has focused on whether restoring NAD+ levels can support these processes as they decline with age.
03 / EVIDENCE
What the research shows
Animal studies suggest raising NAD+ may support metabolism and healthy aging. In people, studies of NAD+ precursors show they can raise NAD+ levels, but consistent improvements in energy, longevity, or performance have not been established. Direct NAD+ therapy has limited published human data.
04 / FIT
Who it may help
- Adults interested in a supervised healthy-aging plan
- People who understand the evidence is still developing
- Patients pairing it with labs, nutrition, sleep, and activity
05 / CAUTION
Who should avoid it
- Pregnancy or breastfeeding
- Active cancer (discuss with your provider)
- Anyone unable to attend follow-up
06 / SAFETY
Possible side effects
- Flushing, nausea, or stomach cramping — especially with faster IV infusions
- Chest tightness or lightheadedness during infusion (slowing the rate usually helps)
- Injection-site discomfort
- Headache or fatigue
This is not a complete list. Your provider will review risks, benefits, and alternatives with you before starting any treatment.
QUESTIONS
Good to know.
Is NAD+ a peptide? +
No. It is a coenzyme, but it is commonly discussed alongside peptide therapies for healthy aging.
Injection or IV — which is better? +
Each has trade-offs in time, comfort, and cost. Your provider will help you choose what fits your goals.
Will I feel a difference? +
Some people report more energy; others notice little. Results vary, and the research is still developing.
How do I get started? +
Complete a short Get Started form. A licensed provider in your state will review your goals and history by telehealth, order labs if needed, and decide whether NAD+ or another option is appropriate.
KEEP LEARNING
Related therapies.
HEALTHY AGING & ENERGYHEALTHY AGING & ENERGYWEIGHT MANAGEMENT
Glutathione
Your body's main antioxidant — a small three–amino acid peptide that helps protect cells from oxidative stress.
Sermorelin
A peptide that encourages your pituitary gland to release more of your own growth hormone.
Semaglutide
A once-weekly GLP-1 medication that helps regulate appetite and blood sugar, used as part of a medical weight-management plan.
EDUCATIONAL INFORMATION
This page is for general education and is not medical advice. NAD+ requires a prescription and is provided only after evaluation by a licensed provider when appropriate. When a compounded formulation is prescribed, it is prepared by a licensed U.S. pharmacy for you specifically. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.