PEPTIDE THERAPY / HEALTHY AGING & ENERGY
Sermorelin
A peptide that encourages your pituitary gland to release more of your own growth hormone.
- STATUS
- Previously FDA-approved (brand discontinued for business reasons, not safety). Available today as a compounded medication, which is not FDA-approved.
- FORMS
- Injection · Other compounded forms may be available
- ACCESS
- Prescription only · Telehealth in all 50 states
KEY TAKEAWAYS
- Signals the body to make its own growth hormone rather than replacing it
- Studied for adult growth-hormone decline
- Evidence for anti-aging benefits is limited
01 / OVERVIEW
What it is
Sermorelin is a shortened version of growth hormone–releasing hormone (GHRH), the natural signal from the brain that tells the pituitary gland to release growth hormone. It was once FDA-approved to evaluate and treat growth-hormone deficiency in children.
02 / MECHANISM
How it works
Instead of supplying growth hormone directly, sermorelin stimulates the pituitary to release it in the body's natural pulses. Because the body's own feedback loops stay in place, the effect is generally gentler than taking growth hormone itself.
03 / EVIDENCE
What the research shows
Sermorelin has been studied as an approach to age-related decline in growth hormone, with reported improvements in markers such as IGF-1. Claims about energy, sleep, body composition, and recovery come largely from small studies and clinical experience; large, long-term trials in healthy adults are lacking.
04 / FIT
Who it may help
- Adults with symptoms and labs consistent with lower growth-hormone activity
- People looking for a gradual, supervised approach to healthy aging
- Patients willing to complete baseline and follow-up labs
05 / CAUTION
Who should avoid it
- Active cancer or a history of certain cancers (discuss with your provider)
- Pregnancy or breastfeeding
- Untreated thyroid disorders
- Known allergy to sermorelin
06 / SAFETY
Possible side effects
- Injection-site redness, swelling, or pain
- Flushing, headache, or dizziness
- Trouble sleeping or changes in mood (uncommon)
This is not a complete list. Your provider will review risks, benefits, and alternatives with you before starting any treatment.
EDUCATIONAL INFORMATIONThis page is for general education and is not medical advice. Sermorelin requires a prescription and is provided only after evaluation by a licensed provider when appropriate. When a compounded formulation is prescribed, it is prepared by a licensed U.S. pharmacy for you specifically. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.